F344-0395 Screening compound: 1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[1-(4-methylbenzoyl)piperidin-4-yl]ethan-1-one

F344-0395 Screening compound: 1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[1-(4-methylbenzoyl)piperidin-4-yl]ethan-1-one
F344-0395 Screening compound: 1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[1-(4-methylbenzoyl)piperidin-4-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F344-0395
1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[1-(4-methylbenzoyl)piperidin-4-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F344-0395

Molecular Formula

C26H33N3O3 (C26 H33 N3 O3)

Compound Name

1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[1-(4-methylbenzoyl)piperidin-4-yl]ethan-1-one

IUPAC name

1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[1-(4-methylbenzoyl)piperidin-4-yl]ethan-1-one

SMILES

Cc(cc1)ccc1C(N1CCC(CC(N(CC2)CCN2c(cc2)ccc2OC)=O)CC1)=O

InChI

InChI=1S/C26H33N3O3/c1-20-3-5-22(6-4-20)26(31)29-13-11-21(12-14-29)19-25(30)28-17-15-27(16-18-28)23-7-9-24(32-2)10-8-23/h3-10,21H,11-19H2,1-2H3

InChI Key

CMANWDMTAAHIGC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14951010

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.636

Distribution Coefficient, logD

3.635

Water Solubility, LogSw

-3.72

Polar Surface Area

43.812

Acid Dissociation Constant (pKa)

24.23

Base Dissociation Constant (pKb)

7.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

F344-0395 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with F344-0395 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F344-0395?
Check Price and Availability of F344-0395, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F344-0395 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F344-0395
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F344-0395
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F344-0395 available by request