F345-0187 Screening compound: N-(3-chlorophenyl)-4-({[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]carbamoyl}methyl)piperidine-1-carboxamide

F345-0187 Screening compound: N-(3-chlorophenyl)-4-({[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]carbamoyl}methyl)piperidine-1-carboxamide
F345-0187 Screening compound: N-(3-chlorophenyl)-4-({[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]carbamoyl}methyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F345-0187
N-(3-chlorophenyl)-4-({[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]carbamoyl}methyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F345-0187

Molecular Formula

C26H33ClN4O2 (C26 H33 ClN4 O2)

Compound Name

N-(3-chlorophenyl)-4-({[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]carbamoyl}methyl)piperidine-1-carboxamide

IUPAC name

N-(3-chlorophenyl)-4-({[3-(1234-tetrahydroisoquinolin-2-yl)propyl]carbamoyl}methyl)piperidine-1-carboxamide

SMILES

O=C(CC(CC1)CCN1C(Nc1cccc(Cl)c1)=O)NCCCN(CC1)Cc2c1cccc2

InChI

InChI=1S/C26H33ClN4O2/c27-23-7-3-8-24(18-23)29-26(33)31-15-9-20(10-16-31)17-25(32)28-12-4-13-30-14-11-21-5-1-2-6-22(21)19-30/h1-3,5-8,18,20H,4,9-17,19H2,(H,28,32)(H,29,33)

InChI Key

ICNRLDHXDJJHBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27117128

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.03

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.035

Distribution Coefficient, logD

2.831

Water Solubility, LogSw

-4.30

Polar Surface Area

53.393

Acid Dissociation Constant (pKa)

12.15

Base Dissociation Constant (pKb)

8.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

F345-0187 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Immune system
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F345-0187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F345-0187?
Check Price and Availability of F345-0187, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F345-0187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F345-0187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F345-0187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F345-0187 available by request