F345-0399 Screening compound: 4-({[(3-fluorophenyl)methyl]carbamoyl}methyl)-N-(3,4,5-trimethoxyphenyl)piperidine-1-carboxamide

F345-0399 Screening compound: 4-({[(3-fluorophenyl)methyl]carbamoyl}methyl)-N-(3,4,5-trimethoxyphenyl)piperidine-1-carboxamide
F345-0399 Screening compound: 4-({[(3-fluorophenyl)methyl]carbamoyl}methyl)-N-(3,4,5-trimethoxyphenyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F345-0399
4-({[(3-fluorophenyl)methyl]carbamoyl}methyl)-N-(3,4,5-trimethoxyphenyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F345-0399

Molecular Formula

C24H30FN3O5 (C24 H30 FN3 O5)

Compound Name

4-({[(3-fluorophenyl)methyl]carbamoyl}methyl)-N-(3,4,5-trimethoxyphenyl)piperidine-1-carboxamide

IUPAC name

4-({[(3-fluorophenyl)methyl]carbamoyl}methyl)-N-(345-trimethoxyphenyl)piperidine-1-carboxamide

SMILES

COc1cc(NC(N2CCC(CC(NCc3cccc(F)c3)=O)CC2)=O)cc(OC)c1OC

InChI

InChI=1S/C24H30FN3O5/c1-31-20-13-19(14-21(32-2)23(20)33-3)27-24(30)28-9-7-16(8-10-28)12-22(29)26-15-17-5-4-6-18(25)11-17/h4-6,11,13-14,16H,7-10,12,15H2,1-3H3,(H,26,29)(H,27,30)

InChI Key

QYHSXHBTSMMSPH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27117212

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.733

Distribution Coefficient, logD

2.733

Water Solubility, LogSw

-3.22

Polar Surface Area

72.885

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

0.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

F345-0399 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F345-0399 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F345-0399?
Check Price and Availability of F345-0399, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F345-0399 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F345-0399
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F345-0399
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F345-0399 available by request