F358-0425 Screening compound: N-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]-3,5-dimethoxybenzamide

F358-0425 Screening compound: N-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]-3,5-dimethoxybenzamide
F358-0425 Screening compound: N-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]-3,5-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F358-0425
N-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]-3,5-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F358-0425

Molecular Formula

C27H22ClN5O4 (C27 H22 ClN5 O4)

Compound Name

N-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]-3,5-dimethoxybenzamide

IUPAC name

N-[4-({4-[3-(4-chlorophenyl)-124-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]-35-dimethoxybenzamide

SMILES

COc1cc(C(Nc2ccc(Cn3cnc(-c4nc(-c(cc5)ccc5Cl)no4)c3)cc2)=O)cc(OC)c1

InChI

InChI=1S/C27H22ClN5O4/c1-35-22-11-19(12-23(13-22)36-2)26(34)30-21-9-3-17(4-10-21)14-33-15-24(29-16-33)27-31-25(32-37-27)18-5-7-20(28)8-6-18/h3-13,15-16H,14H2,1-2H3,(H,30,34)

InChI Key

ODHLHIBMRDNIOY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27118814

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

515.96

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

5.718

Distribution Coefficient, logD

5.718

Water Solubility, LogSw

-6.07

Polar Surface Area

81.886

Acid Dissociation Constant (pKa)

12.30

Base Dissociation Constant (pKb)

2.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

F358-0425 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F358-0425 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F358-0425?
Check Price and Availability of F358-0425, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F358-0425 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F358-0425
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F358-0425
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F358-0425 available by request