F366-0169 Screening compound: 4-[(4-fluorophenyl)methyl]-2-[2-(5-methoxy-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

F366-0169 Screening compound: 4-[(4-fluorophenyl)methyl]-2-[2-(5-methoxy-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione
F366-0169 Screening compound: 4-[(4-fluorophenyl)methyl]-2-[2-(5-methoxy-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F366-0169
4-[(4-fluorophenyl)methyl]-2-[2-(5-methoxy-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F366-0169

Molecular Formula

C27H20FN5O4 (C27 H20 FN5 O4)

Compound Name

4-[(4-fluorophenyl)methyl]-2-[2-(5-methoxy-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

IUPAC name

4-[(4-fluorophenyl)methyl]-2-[2-(5-methoxy-1H-indol-3-yl)-2-oxoethyl]-1H2H4H5H-[124]triazolo[43-a]quinazoline-15-dione

SMILES

COc(cc1)cc2c1[nH]cc2C(CN(C(N1c2c3cccc2)=O)N=C1N(Cc(cc1)ccc1F)C3=O)=O

InChI

InChI=1S/C27H20FN5O4/c1-37-18-10-11-22-20(12-18)21(13-29-22)24(34)15-32-27(36)33-23-5-3-2-4-19(23)25(35)31(26(33)30-32)14-16-6-8-17(28)9-7-16/h2-13,29H,14-15H2,1H3

InChI Key

KDGFLHPVMPDHGW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119619

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.938

Distribution Coefficient, logD

3.938

Water Solubility, LogSw

-4.20

Polar Surface Area

78.597

Acid Dissociation Constant (pKa)

15.97

Base Dissociation Constant (pKb)

-1.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

F366-0169 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Others
  • Phosphatases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F366-0169 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F366-0169?
Check Price and Availability of F366-0169, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F366-0169 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F366-0169
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F366-0169
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F366-0169 available by request