F373-0046 Screening compound: 5-cyclobutyl-3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazole

F373-0046 Screening compound: 5-cyclobutyl-3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazole
F373-0046 Screening compound: 5-cyclobutyl-3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound F373-0046
5-cyclobutyl-3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F373-0046

Molecular Formula

C16H19N3O (C16 H19 N3 O)

Compound Name

5-cyclobutyl-3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazole

IUPAC name

5-cyclobutyl-3-[4-(pyrrolidin-1-yl)phenyl]-124-oxadiazole

SMILES

C(C1)CC1c1nc(-c(cc2)ccc2N2CCCC2)no1

InChI

InChI=1S/C16H19N3O/c1-2-11-19(10-1)14-8-6-12(7-9-14)15-17-16(20-18-15)13-4-3-5-13/h6-9,13H,1-5,10-11H2

InChI Key

CDQHPZHQMLWPLB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27120590

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

269.35

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.277

Distribution Coefficient, logD

4.277

Water Solubility, LogSw

-4.28

Polar Surface Area

35.986

Acid Dissociation Constant (pKa)

26.82

Base Dissociation Constant (pKb)

1.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

F373-0046 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Cardiovascular Library (22201 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F373-0046 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F373-0046?
Check Price and Availability of F373-0046, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F373-0046 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F373-0046
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F373-0046
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F373-0046 available by request