F387-1498 Screening compound: N-(1-benzylpiperidin-4-yl)-3-[(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

F387-1498 Screening compound: N-(1-benzylpiperidin-4-yl)-3-[(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide
F387-1498 Screening compound: N-(1-benzylpiperidin-4-yl)-3-[(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F387-1498
N-(1-benzylpiperidin-4-yl)-3-[(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F387-1498

Molecular Formula

C25H26N6O3 (C25 H26 N6 O3)

Compound Name

N-(1-benzylpiperidin-4-yl)-3-[(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-3-[(2-methyl-4-oxo-34-dihydroquinazolin-3-yl)methyl]-124-oxadiazole-5-carboxamide

SMILES

CC(N1Cc2noc(C(NC3CCN(Cc4ccccc4)CC3)=O)n2)=Nc(cccc2)c2C1=O

InChI

InChI=1S/C25H26N6O3/c1-17-26-21-10-6-5-9-20(21)25(33)31(17)16-22-28-24(34-29-22)23(32)27-19-11-13-30(14-12-19)15-18-7-3-2-4-8-18/h2-10,19H,11-16H2,1H3,(H,27,32)

InChI Key

FDRYZCOXBUVSHA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27122250

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.938

Distribution Coefficient, logD

0.492

Water Solubility, LogSw

-2.89

Polar Surface Area

85.004

Acid Dissociation Constant (pKa)

14.57

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

F387-1498 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F387-1498 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F387-1498?
Check Price and Availability of F387-1498, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F387-1498 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F387-1498
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F387-1498
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F387-1498 available by request