F388-0161 Screening compound: N-(3-chloro-4-methoxyphenyl)-3-(4-oxo-3,4-dihydroquinazolin-3-yl)propanamide

F388-0161 Screening compound: N-(3-chloro-4-methoxyphenyl)-3-(4-oxo-3,4-dihydroquinazolin-3-yl)propanamide
F388-0161 Screening compound: N-(3-chloro-4-methoxyphenyl)-3-(4-oxo-3,4-dihydroquinazolin-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F388-0161
N-(3-chloro-4-methoxyphenyl)-3-(4-oxo-3,4-dihydroquinazolin-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F388-0161

Molecular Formula

C18H16ClN3O3 (C18 H16 ClN3 O3)

Compound Name

N-(3-chloro-4-methoxyphenyl)-3-(4-oxo-3,4-dihydroquinazolin-3-yl)propanamide

IUPAC name

N-(3-chloro-4-methoxyphenyl)-3-(4-oxo-34-dihydroquinazolin-3-yl)propanamide

SMILES

COc(ccc(NC(CCN(C=Nc1c2cccc1)C2=O)=O)c1)c1Cl

InChI

InChI=1S/C18H16ClN3O3/c1-25-16-7-6-12(10-14(16)19)21-17(23)8-9-22-11-20-15-5-3-2-4-13(15)18(22)24/h2-7,10-11H,8-9H2,1H3,(H,21,23)

InChI Key

VNJVTYCJCYTLOS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06774505

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.8

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.291

Distribution Coefficient, logD

2.289

Water Solubility, LogSw

-3.49

Polar Surface Area

57.097

Acid Dissociation Constant (pKa)

9.98

Base Dissociation Constant (pKb)

1.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

F388-0161 in Drug Discovery

Included in Screening Libraries

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F388-0161 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F388-0161?
Check Price and Availability of F388-0161, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F388-0161 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F388-0161
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F388-0161
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F388-0161 available by request