F424-1146 Screening compound: 2-{[2-(3,4-dimethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-7-yl]sulfanyl}-N-(4-fluorophenyl)-N-methylacetamide

F424-1146 Screening compound: 2-{[2-(3,4-dimethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-7-yl]sulfanyl}-N-(4-fluorophenyl)-N-methylacetamide
F424-1146 Screening compound: 2-{[2-(3,4-dimethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-7-yl]sulfanyl}-N-(4-fluorophenyl)-N-methylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F424-1146
2-{[2-(3,4-dimethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-7-yl]sulfanyl}-N-(4-fluorophenyl)-N-methylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F424-1146

Molecular Formula

C22H20FN5O4S (C22 H20 FN5 O4 S)

Compound Name

2-{[2-(3,4-dimethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-7-yl]sulfanyl}-N-(4-fluorophenyl)-N-methylacetamide

IUPAC name

2-{[2-(34-dimethoxyphenyl)-4-oxo-4H5H-pyrazolo[15-d][124]triazin-7-yl]sulfanyl}-N-(4-fluorophenyl)-N-methylacetamide

SMILES

CN(C(CSC(n(c1c2)nc2-c(cc2)cc(OC)c2OC)=NNC1=O)=O)c(cc1)ccc1F

InChI

InChI=1S/C22H20FN5O4S/c1-27(15-7-5-14(23)6-8-15)20(29)12-33-22-25-24-21(30)17-11-16(26-28(17)22)13-4-9-18(31-2)19(10-13)32-3/h4-11H,12H2,1-3H3,(H,24,30)

InChI Key

DSRSVXWDKAOSHD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27127059

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.580

Distribution Coefficient, logD

2.578

Water Solubility, LogSw

-3.03

Polar Surface Area

81.688

Acid Dissociation Constant (pKa)

9.85

Base Dissociation Constant (pKb)

2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

F424-1146 in Drug Discovery

Included in Screening Libraries

ACE2 Library (3043 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CORONAVIRUS Library (20774 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with F424-1146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F424-1146?
Check Price and Availability of F424-1146, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F424-1146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F424-1146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F424-1146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F424-1146 available by request