F426-0022 Screening compound: N-[2-(1-cyclohexenyl)ethyl]-1-[6-(4-fluorophenyl)-4-pyrimidinyl]-4-piperidinecarboxamide

F426-0022 Screening compound: N-[2-(1-cyclohexenyl)ethyl]-1-[6-(4-fluorophenyl)-4-pyrimidinyl]-4-piperidinecarboxamide
F426-0022 Screening compound: N-[2-(1-cyclohexenyl)ethyl]-1-[6-(4-fluorophenyl)-4-pyrimidinyl]-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F426-0022
N-[2-(1-cyclohexenyl)ethyl]-1-[6-(4-fluorophenyl)-4-pyrimidinyl]-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F426-0022

Molecular Formula

C24H29FN4O (C24 H29 FN4 O)

Compound Name

N-[2-(1-cyclohexenyl)ethyl]-1-[6-(4-fluorophenyl)-4-pyrimidinyl]-4-piperidinecarboxamide

IUPAC name

N-[2-(cyclohex-1-en-1-yl)ethyl]-1-[6-(4-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1cc(-c(cc2)ccc2F)ncn1)NCCC1=CCCCC1

InChI

InChI=1S/C24H29FN4O/c25-21-8-6-19(7-9-21)22-16-23(28-17-27-22)29-14-11-20(12-15-29)24(30)26-13-10-18-4-2-1-3-5-18/h4,6-9,16-17,20H,1-3,5,10-15H2,(H,26,30)

InChI Key

NDWZKAJGZKEBMY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27127119

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.791

Distribution Coefficient, logD

4.790

Water Solubility, LogSw

-4.80

Polar Surface Area

47.140

Acid Dissociation Constant (pKa)

14.61

Base Dissociation Constant (pKb)

4.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.83

F426-0022 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F426-0022 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F426-0022?
Check Price and Availability of F426-0022, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F426-0022 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F426-0022
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F426-0022
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F426-0022 available by request