F449-1421 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[3-(pyrrolidin-1-yl)propyl]acetamide

F449-1421 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[3-(pyrrolidin-1-yl)propyl]acetamide
F449-1421 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[3-(pyrrolidin-1-yl)propyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F449-1421
2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[3-(pyrrolidin-1-yl)propyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F449-1421

Molecular Formula

C25H37N7O2S (C25 H37 N7 O2 S)

Compound Name

2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[3-(pyrrolidin-1-yl)propyl]acetamide

IUPAC name

2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[21-b][134]thiadiazol-2-yl](methyl)amino}-N-[3-(pyrrolidin-1-yl)propyl]acetamide

SMILES

CC(C)(C)Nc1c(-c(cc2)ccc2OC)nc2sc(N(C)CC(NCCCN3CCCC3)=O)nn12

InChI

InChI=1S/C25H37N7O2S/c1-25(2,3)28-22-21(18-9-11-19(34-5)12-10-18)27-23-32(22)29-24(35-23)30(4)17-20(33)26-13-8-16-31-14-6-7-15-31/h9-12,28H,6-8,13-17H2,1-5H3,(H,26,33)

InChI Key

NJUCISMPEBIVII-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27129674

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.68

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.357

Distribution Coefficient, logD

0.267

Water Solubility, LogSw

-3.53

Polar Surface Area

69.487

Acid Dissociation Constant (pKa)

15.60

Base Dissociation Constant (pKb)

10.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.00

F449-1421 in Drug Discovery

Included in Screening Libraries

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with F449-1421 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F449-1421?
Check Price and Availability of F449-1421, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F449-1421 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F449-1421
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F449-1421
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F449-1421 available by request