F464-0370 Screening compound: 2-[9-chloro-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-cyclohexylacetamide

F464-0370 Screening compound: 2-[9-chloro-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-cyclohexylacetamide
F464-0370 Screening compound: 2-[9-chloro-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-cyclohexylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F464-0370
2-[9-chloro-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-cyclohexylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F464-0370

Molecular Formula

C18H18ClN3O2S (C18 H18 ClN3 O2 S)

Compound Name

2-[9-chloro-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-cyclohexylacetamide

IUPAC name

2-{13-chloro-6-oxo-8-thia-35-diazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)3911-pentaen-5-yl}-N-cyclohexylacetamide

SMILES

O=C(CN(C=Nc1c2sc3cccc(Cl)c13)C2=O)NC1CCCCC1

InChI

InChI=1S/C18H18ClN3O2S/c19-12-7-4-8-13-15(12)16-17(25-13)18(24)22(10-20-16)9-14(23)21-11-5-2-1-3-6-11/h4,7-8,10-11H,1-3,5-6,9H2,(H,21,23)

InChI Key

NGKUSNPVOCHKKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27131104

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.596

Distribution Coefficient, logD

3.596

Water Solubility, LogSw

-3.86

Polar Surface Area

49.030

Acid Dissociation Constant (pKa)

15.87

Base Dissociation Constant (pKb)

1.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

F464-0370 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F464-0370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F464-0370?
Check Price and Availability of F464-0370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F464-0370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F464-0370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F464-0370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F464-0370 available by request