F526-0003 Screening compound: 7-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

F526-0003 Screening compound: 7-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
F526-0003 Screening compound: 7-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F526-0003
7-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F526-0003

Molecular Formula

C21H18FN5O3S2 (C21 H18 FN5 O3 S2)

Compound Name

7-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

IUPAC name

7-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-2-phenyl-5H-[134]thiadiazolo[32-a]pyrimidin-5-one

SMILES

O=C1N2N=C(c3ccccc3)SC2=NC(N(CC2)CCN2S(c(cc2)ccc2F)(=O)=O)=C1

InChI

InChI=1S/C21H18FN5O3S2/c22-16-6-8-17(9-7-16)32(29,30)26-12-10-25(11-13-26)18-14-19(28)27-21(23-18)31-20(24-27)15-4-2-1-3-5-15/h1-9,14H,10-13H2

InChI Key

CWMFZBOWHSDABO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14958030

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.54

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.907

Distribution Coefficient, logD

2.900

Water Solubility, LogSw

-3.37

Polar Surface Area

72.887

Acid Dissociation Constant (pKa)

28.41

Base Dissociation Constant (pKb)

5.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

F526-0003 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F526-0003 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F526-0003?
Check Price and Availability of F526-0003, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F526-0003 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F526-0003
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F526-0003
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F526-0003 available by request