F545-2173 Screening compound: 3-{3-[3-(pyrrolidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}-4,5,6,7-tetrahydro-1H-indazole

F545-2173 Screening compound: 3-{3-[3-(pyrrolidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}-4,5,6,7-tetrahydro-1H-indazole
F545-2173 Screening compound: 3-{3-[3-(pyrrolidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}-4,5,6,7-tetrahydro-1H-indazole alternative view

Chemical Structure Depiction of ChemDiv screening compound F545-2173
3-{3-[3-(pyrrolidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}-4,5,6,7-tetrahydro-1H-indazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F545-2173

Molecular Formula

C20H21N5O2 (C20 H21 N5 O2)

Compound Name

3-{3-[3-(pyrrolidine-1-carbonyl)phenyl]-1,2,4-oxadiazol-5-yl}-4,5,6,7-tetrahydro-1H-indazole

IUPAC name

3-{3-[3-(pyrrolidine-1-carbonyl)phenyl]-124-oxadiazol-5-yl}-4567-tetrahydro-1H-indazole

SMILES

O=C(c1cc(-c2noc(-c3n[nH]c4c3CCCC4)n2)ccc1)N1CCCC1

InChI

InChI=1S/C20H21N5O2/c26-20(25-10-3-4-11-25)14-7-5-6-13(12-14)18-21-19(27-24-18)17-15-8-1-2-9-16(15)22-23-17/h5-7,12H,1-4,8-11H2,(H,22,23)

InChI Key

UGZCEEGDCSZRJS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27175554

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

363.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.185

Distribution Coefficient, logD

3.185

Water Solubility, LogSw

-3.37

Polar Surface Area

73.612

Acid Dissociation Constant (pKa)

14.65

Base Dissociation Constant (pKb)

0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

F545-2173 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F545-2173 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F545-2173?
Check Price and Availability of F545-2173, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F545-2173 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F545-2173
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F545-2173
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F545-2173 available by request