F548-2049 Screening compound: 2,3-dihydro-1H-indol-1-yl{6-[3,4-dihydro-2(1H)-isoquinolinyl]-3-pyridazinyl}methanone

F548-2049 Screening compound: 2,3-dihydro-1H-indol-1-yl{6-[3,4-dihydro-2(1H)-isoquinolinyl]-3-pyridazinyl}methanone
F548-2049 Screening compound: 2,3-dihydro-1H-indol-1-yl{6-[3,4-dihydro-2(1H)-isoquinolinyl]-3-pyridazinyl}methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound F548-2049
2,3-dihydro-1H-indol-1-yl{6-[3,4-dihydro-2(1H)-isoquinolinyl]-3-pyridazinyl}methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F548-2049

Molecular Formula

C22H20N4O (C22 H20 N4 O)

Compound Name

2,3-dihydro-1H-indol-1-yl{6-[3,4-dihydro-2(1H)-isoquinolinyl]-3-pyridazinyl}methanone

IUPAC name

n/a

SMILES

O=C(c(cc1)nnc1N(CC1)Cc2c1cccc2)N(CC1)c2c1cccc2

InChI

InChI=1S/C22H20N4O/c27-22(26-14-12-17-6-3-4-8-20(17)26)19-9-10-21(24-23-19)25-13-11-16-5-1-2-7-18(16)15-25/h1-10H,11-15H2

InChI Key

LYGJDJWQKPBFTJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27175659

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.702

Distribution Coefficient, logD

3.702

Water Solubility, LogSw

-3.91

Polar Surface Area

40.238

Acid Dissociation Constant (pKa)

20.98

Base Dissociation Constant (pKb)

1.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

F548-2049 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F548-2049 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F548-2049?
Check Price and Availability of F548-2049, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F548-2049 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F548-2049
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F548-2049
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F548-2049 available by request