F548-2083 Screening compound: 1-[6-(4-benzylpiperazin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole

F548-2083 Screening compound: 1-[6-(4-benzylpiperazin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole
F548-2083 Screening compound: 1-[6-(4-benzylpiperazin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound F548-2083
1-[6-(4-benzylpiperazin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F548-2083

Molecular Formula

C24H25N5O (C24 H25 N5 O)

Compound Name

1-[6-(4-benzylpiperazin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole

IUPAC name

1-[6-(4-benzylpiperazin-1-yl)pyridazine-3-carbonyl]-23-dihydro-1H-indole

SMILES

O=C(c(cc1)nnc1N1CCN(Cc2ccccc2)CC1)N(CC1)c2c1cccc2

InChI

InChI=1S/C24H25N5O/c30-24(29-13-12-20-8-4-5-9-22(20)29)21-10-11-23(26-25-21)28-16-14-27(15-17-28)18-19-6-2-1-3-7-19/h1-11H,12-18H2

InChI Key

RGFXWAMSPZPKFD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27175662

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.266

Distribution Coefficient, logD

3.158

Water Solubility, LogSw

-3.23

Polar Surface Area

44.117

Acid Dissociation Constant (pKa)

24.26

Base Dissociation Constant (pKb)

6.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

F548-2083 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F548-2083 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F548-2083?
Check Price and Availability of F548-2083, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F548-2083 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F548-2083
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F548-2083
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F548-2083 available by request