F548-2088 Screening compound: 1-[6-(4-benzylpiperidin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole

F548-2088 Screening compound: 1-[6-(4-benzylpiperidin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole
F548-2088 Screening compound: 1-[6-(4-benzylpiperidin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound F548-2088
1-[6-(4-benzylpiperidin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F548-2088

Molecular Formula

C25H26N4O (C25 H26 N4 O)

Compound Name

1-[6-(4-benzylpiperidin-1-yl)pyridazine-3-carbonyl]-2,3-dihydro-1H-indole

IUPAC name

1-[6-(4-benzylpiperidin-1-yl)pyridazine-3-carbonyl]-23-dihydro-1H-indole

SMILES

O=C(c(cc1)nnc1N1CCC(Cc2ccccc2)CC1)N(CC1)c2c1cccc2

InChI

InChI=1S/C25H26N4O/c30-25(29-17-14-21-8-4-5-9-23(21)29)22-10-11-24(27-26-22)28-15-12-20(13-16-28)18-19-6-2-1-3-7-19/h1-11,20H,12-18H2

InChI Key

MNWRLKRHTLAFKE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27175663

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.921

Distribution Coefficient, logD

4.921

Water Solubility, LogSw

-4.88

Polar Surface Area

40.305

Acid Dissociation Constant (pKa)

23.86

Base Dissociation Constant (pKb)

3.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

F548-2088 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Kinases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F548-2088 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F548-2088?
Check Price and Availability of F548-2088, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F548-2088 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F548-2088
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F548-2088
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F548-2088 available by request