F584-1646 Screening compound: N5-(3-chloro-4-fluorophenyl)-1-methyl-N3-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3,5-dicarboxamide

F584-1646 Screening compound: N5-(3-chloro-4-fluorophenyl)-1-methyl-N3-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3,5-dicarboxamide
F584-1646 Screening compound: N5-(3-chloro-4-fluorophenyl)-1-methyl-N3-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3,5-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F584-1646
N5-(3-chloro-4-fluorophenyl)-1-methyl-N3-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3,5-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F584-1646

Molecular Formula

C21H19ClFN5O2 (C21 H19 ClFN5 O2)

Compound Name

N5-(3-chloro-4-fluorophenyl)-1-methyl-N3-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3,5-dicarboxamide

IUPAC name

N5-(3-chloro-4-fluorophenyl)-1-methyl-N3-phenyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-35-dicarboxamide

SMILES

Cn1nc(C(Nc2ccccc2)=O)c(C2)c1CCN2C(Nc(cc1)cc(Cl)c1F)=O

InChI

InChI=1S/C21H19ClFN5O2/c1-27-18-9-10-28(21(30)25-14-7-8-17(23)16(22)11-14)12-15(18)19(26-27)20(29)24-13-5-3-2-4-6-13/h2-8,11H,9-10,12H2,1H3,(H,24,29)(H,25,30)

InChI Key

YGZVVMYEJYSTSD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27177498

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.87

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.134

Distribution Coefficient, logD

3.133

Water Solubility, LogSw

-3.60

Polar Surface Area

63.478

Acid Dissociation Constant (pKa)

10.39

Base Dissociation Constant (pKb)

0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

F584-1646 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Anti-HIV1 Library (19540 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F584-1646 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F584-1646?
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What is the minimum amount of F584-1646 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F584-1646
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F584-1646
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F584-1646 available by request