F624-4789 Screening compound: 1-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-4-phenylpiperazine

F624-4789 Screening compound: 1-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-4-phenylpiperazine
F624-4789 Screening compound: 1-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F624-4789
1-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F624-4789

Molecular Formula

C25H22FN5O (C25 H22 FN5 O)

Compound Name

1-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-4-phenylpiperazine

IUPAC name

1-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-4-phenylpiperazine

SMILES

O=C(c(cc1-c2ccncc2)nn1-c(cc1)ccc1F)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C25H22FN5O/c26-20-6-8-22(9-7-20)31-24(19-10-12-27-13-11-19)18-23(28-31)25(32)30-16-14-29(15-17-30)21-4-2-1-3-5-21/h1-13,18H,14-17H2

InChI Key

JBGPADPYAGTXNW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27179634

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.950

Distribution Coefficient, logD

3.950

Water Solubility, LogSw

-3.97

Polar Surface Area

42.398

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

3.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

F624-4789 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

SH2 Library (10483 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F624-4789 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F624-4789?
Check Price and Availability of F624-4789, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F624-4789 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F624-4789
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F624-4789
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F624-4789 available by request