F667-0269 Screening compound: 1,3,6-trimethyl-5-{4-[4-(morpholin-4-yl)-4-oxobutanoyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione

F667-0269 Screening compound: 1,3,6-trimethyl-5-{4-[4-(morpholin-4-yl)-4-oxobutanoyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione
F667-0269 Screening compound: 1,3,6-trimethyl-5-{4-[4-(morpholin-4-yl)-4-oxobutanoyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F667-0269
1,3,6-trimethyl-5-{4-[4-(morpholin-4-yl)-4-oxobutanoyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F667-0269

Molecular Formula

C19H29N5O5 (C19 H29 N5 O5)

Compound Name

1,3,6-trimethyl-5-{4-[4-(morpholin-4-yl)-4-oxobutanoyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

136-trimethyl-5-{4-[4-(morpholin-4-yl)-4-oxobutanoyl]piperazin-1-yl}-1234-tetrahydropyrimidine-24-dione

SMILES

CC(N(C)C(N(C)C1=O)=O)=C1N(CC1)CCN1C(CCC(N1CCOCC1)=O)=O

InChI

InChI=1S/C19H29N5O5/c1-14-17(18(27)21(3)19(28)20(14)2)24-8-6-22(7-9-24)15(25)4-5-16(26)23-10-12-29-13-11-23/h4-13H2,1-3H3

InChI Key

ZGEPGPQUKPTQGI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27183164

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

-1.026

Distribution Coefficient, logD

-1.028

Water Solubility, LogSw

0.23

Polar Surface Area

75.443

Acid Dissociation Constant (pKa)

24.02

Base Dissociation Constant (pKb)

5.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

68.40

F667-0269 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

GPCR Targeted Library (31838 compounds)

Nucleoside Mimetics Library (2197 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Cancer
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F667-0269 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F667-0269?
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What is the minimum amount of F667-0269 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F667-0269
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F667-0269
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F667-0269 available by request