F707-1772 Screening compound: 1-{1-[3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidine-4-carbonyl}-4-(pyridin-2-yl)piperazine

F707-1772 Screening compound: 1-{1-[3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidine-4-carbonyl}-4-(pyridin-2-yl)piperazine
F707-1772 Screening compound: 1-{1-[3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidine-4-carbonyl}-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F707-1772
1-{1-[3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidine-4-carbonyl}-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F707-1772

Molecular Formula

C27H30N8O2 (C27 H30 N8 O2)

Compound Name

1-{1-[3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidine-4-carbonyl}-4-(pyridin-2-yl)piperazine

IUPAC name

1-{1-[3-(4-methoxyphenyl)-[124]triazolo[43-b]pyridazin-6-yl]piperidine-4-carbonyl}-4-(pyridin-2-yl)piperazine

SMILES

COc(cc1)ccc1-c1nnc(cc2)n1nc2N(CC1)CCC1C(N(CC1)CCN1c1ncccc1)=O

InChI

InChI=1S/C27H30N8O2/c1-37-22-7-5-20(6-8-22)26-30-29-24-9-10-25(31-35(24)26)32-14-11-21(12-15-32)27(36)34-18-16-33(17-19-34)23-4-2-3-13-28-23/h2-10,13,21H,11-12,14-19H2,1H3

InChI Key

ZBYLGKTUIHUTRC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27186217

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.573

Distribution Coefficient, logD

3.564

Water Solubility, LogSw

-3.35

Polar Surface Area

71.277

Acid Dissociation Constant (pKa)

22.16

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.00

F707-1772 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F707-1772 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F707-1772?
Check Price and Availability of F707-1772, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F707-1772 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F707-1772
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F707-1772
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F707-1772 available by request