F707-3181 Screening compound: 2-[4-(1-{3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidine-4-carbonyl)piperazin-1-yl]pyrimidine

F707-3181 Screening compound: 2-[4-(1-{3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidine-4-carbonyl)piperazin-1-yl]pyrimidine
F707-3181 Screening compound: 2-[4-(1-{3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidine-4-carbonyl)piperazin-1-yl]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound F707-3181
2-[4-(1-{3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidine-4-carbonyl)piperazin-1-yl]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F707-3181

Molecular Formula

C25H27N9O (C25 H27 N9 O)

Compound Name

2-[4-(1-{3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidine-4-carbonyl)piperazin-1-yl]pyrimidine

IUPAC name

2-[4-(1-{3-phenyl-[124]triazolo[43-b]pyridazin-6-yl}piperidine-4-carbonyl)piperazin-1-yl]pyrimidine

SMILES

O=C(C(CC1)CCN1c1nn2c(-c3ccccc3)nnc2cc1)N(CC1)CCN1c1ncccn1

InChI

InChI=1S/C25H27N9O/c35-24(32-15-17-33(18-16-32)25-26-11-4-12-27-25)20-9-13-31(14-10-20)22-8-7-21-28-29-23(34(21)30-22)19-5-2-1-3-6-19/h1-8,11-12,20H,9-10,13-18H2

InChI Key

GUTJFTFJOKDIBS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27186503

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.982

Distribution Coefficient, logD

2.982

Water Solubility, LogSw

-2.93

Polar Surface Area

73.584

Acid Dissociation Constant (pKa)

21.15

Base Dissociation Constant (pKb)

2.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

F707-3181 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Akt-Targeted Library (14764 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F707-3181 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F707-3181?
Check Price and Availability of F707-3181, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F707-3181 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F707-3181
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F707-3181
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F707-3181 available by request