F765-1640 Screening compound: 4-{4-[(4-methylphenyl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-1-carbonyl}benzonitrile

F765-1640 Screening compound: 4-{4-[(4-methylphenyl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-1-carbonyl}benzonitrile
F765-1640 Screening compound: 4-{4-[(4-methylphenyl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-1-carbonyl}benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound F765-1640
4-{4-[(4-methylphenyl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-1-carbonyl}benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F765-1640

Molecular Formula

C23H20N4O (C23 H20 N4 O)

Compound Name

4-{4-[(4-methylphenyl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-1-carbonyl}benzonitrile

IUPAC name

4-{4-[(4-methylphenyl)methyl]-1H2H3H4H-pyrido[23-b]pyrazine-1-carbonyl}benzonitrile

SMILES

Cc1ccc(CN(CC2)c(nccc3)c3N2C(c(cc2)ccc2C#N)=O)cc1

InChI

InChI=1S/C23H20N4O/c1-17-4-6-19(7-5-17)16-26-13-14-27(21-3-2-12-25-22(21)26)23(28)20-10-8-18(15-24)9-11-20/h2-12H,13-14,16H2,1H3

InChI Key

MWTIQVYCFLHAGZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27189631

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.750

Distribution Coefficient, logD

3.749

Water Solubility, LogSw

-3.83

Polar Surface Area

45.581

Acid Dissociation Constant (pKa)

20.98

Base Dissociation Constant (pKb)

4.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

F765-1640 in Drug Discovery

Included in Screening Libraries

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F765-1640 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F765-1640?
Check Price and Availability of F765-1640, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F765-1640 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F765-1640
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F765-1640
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F765-1640 available by request