F807-1481 Screening compound: tert-butyl {6-[4-(2-pyrimidinyl)piperazino]-3-pyridazinyl} sulfone

F807-1481 Screening compound: tert-butyl {6-[4-(2-pyrimidinyl)piperazino]-3-pyridazinyl} sulfone
F807-1481 Screening compound: tert-butyl {6-[4-(2-pyrimidinyl)piperazino]-3-pyridazinyl} sulfone alternative view

Chemical Structure Depiction of ChemDiv screening compound F807-1481
tert-butyl {6-[4-(2-pyrimidinyl)piperazino]-3-pyridazinyl} sulfone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F807-1481

Molecular Formula

C16H22N6O2S (C16 H22 N6 O2 S)

Compound Name

tert-butyl {6-[4-(2-pyrimidinyl)piperazino]-3-pyridazinyl} sulfone

IUPAC name

3-(2-methylpropane-2-sulfonyl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine

SMILES

CC(C)(C)S(c(cc1)nnc1N(CC1)CCN1c1ncccn1)(=O)=O

InChI

InChI=1S/C16H22N6O2S/c1-16(2,3)25(23,24)14-6-5-13(19-20-14)21-9-11-22(12-10-21)15-17-7-4-8-18-15/h4-8H,9-12H2,1-3H3

InChI Key

FQYYDCAKKKZUTB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11996962

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.180

Distribution Coefficient, logD

2.180

Water Solubility, LogSw

-2.34

Polar Surface Area

76.067

Acid Dissociation Constant (pKa)

20.92

Base Dissociation Constant (pKb)

2.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

F807-1481 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F807-1481 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F807-1481?
Check Price and Availability of F807-1481, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F807-1481 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F807-1481
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F807-1481
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F807-1481 available by request