F828-1357 Screening compound: 1-{1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)sulfonyl]piperidine-4-carbonyl}-2-methyl-2,3-dihydro-1H-indole

F828-1357 Screening compound: 1-{1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)sulfonyl]piperidine-4-carbonyl}-2-methyl-2,3-dihydro-1H-indole
F828-1357 Screening compound: 1-{1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)sulfonyl]piperidine-4-carbonyl}-2-methyl-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound F828-1357
1-{1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)sulfonyl]piperidine-4-carbonyl}-2-methyl-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F828-1357

Molecular Formula

C26H30N4O3S (C26 H30 N4 O3 S)

Compound Name

1-{1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)sulfonyl]piperidine-4-carbonyl}-2-methyl-2,3-dihydro-1H-indole

IUPAC name

1-{1-[(35-dimethyl-1-phenyl-1H-pyrazol-4-yl)sulfonyl]piperidine-4-carbonyl}-2-methyl-23-dihydro-1H-indole

SMILES

CC(C1)N(C(C(CC2)CCN2S(c2c(C)n(-c3ccccc3)nc2C)(=O)=O)=O)c2c1cccc2

InChI

InChI=1S/C26H30N4O3S/c1-18-17-22-9-7-8-12-24(22)29(18)26(31)21-13-15-28(16-14-21)34(32,33)25-19(2)27-30(20(25)3)23-10-5-4-6-11-23/h4-12,18,21H,13-17H2,1-3H3/t18-/m0/s1

InChI Key

DKTISCJRHPDBPV-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27196409

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.62

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.223

Distribution Coefficient, logD

3.223

Water Solubility, LogSw

-3.44

Polar Surface Area

60.985

Acid Dissociation Constant (pKa)

22.37

Base Dissociation Constant (pKb)

-0.16

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.50

F828-1357 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F828-1357 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F828-1357?
Check Price and Availability of F828-1357, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F828-1357 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F828-1357
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F828-1357
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F828-1357 available by request