F873-0135 Screening compound: methyl 4-chloro-2-[({3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}carbamoyl)amino]benzoate

F873-0135 Screening compound: methyl 4-chloro-2-[({3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}carbamoyl)amino]benzoate
F873-0135 Screening compound: methyl 4-chloro-2-[({3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}carbamoyl)amino]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound F873-0135
methyl 4-chloro-2-[({3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}carbamoyl)amino]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F873-0135

Molecular Formula

C25H24ClN5O3 (C25 H24 ClN5 O3)

Compound Name

methyl 4-chloro-2-[({3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}carbamoyl)amino]benzoate

IUPAC name

methyl 4-chloro-2-[({3-[2-(4-methylphenyl)-3H-imidazo[45-b]pyridin-3-yl]propyl}carbamoyl)amino]benzoate

SMILES

Cc(cc1)ccc1-c1nc2cccnc2n1CCCNC(Nc(cc(cc1)Cl)c1C(OC)=O)=O

InChI

InChI=1S/C25H24ClN5O3/c1-16-6-8-17(9-7-16)22-29-20-5-3-12-27-23(20)31(22)14-4-13-28-25(33)30-21-15-18(26)10-11-19(21)24(32)34-2/h3,5-12,15H,4,13-14H2,1-2H3,(H2,28,30,33)

InChI Key

NEBQIMMUGGUACN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27201281

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.95

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.778

Distribution Coefficient, logD

4.686

Water Solubility, LogSw

-4.84

Polar Surface Area

73.995

Acid Dissociation Constant (pKa)

8.03

Base Dissociation Constant (pKb)

3.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

F873-0135 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with F873-0135 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F873-0135?
Check Price and Availability of F873-0135, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F873-0135 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F873-0135
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F873-0135
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F873-0135 available by request