F878-0294 Screening compound: N-[4-(5-fluoro-1H-indol-2-yl)phenyl]-1-phenylmethanesulfonamide

F878-0294 Screening compound: N-[4-(5-fluoro-1H-indol-2-yl)phenyl]-1-phenylmethanesulfonamide
F878-0294 Screening compound: N-[4-(5-fluoro-1H-indol-2-yl)phenyl]-1-phenylmethanesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F878-0294
N-[4-(5-fluoro-1H-indol-2-yl)phenyl]-1-phenylmethanesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F878-0294

Molecular Formula

C21H17FN2O2S (C21 H17 FN2 O2 S)

Compound Name

N-[4-(5-fluoro-1H-indol-2-yl)phenyl]-1-phenylmethanesulfonamide

IUPAC name

N-[4-(5-fluoro-1H-indol-2-yl)phenyl]-1-phenylmethanesulfonamide

SMILES

O=S(Cc1ccccc1)(Nc(cc1)ccc1-c1cc(cc(cc2)F)c2[nH]1)=O

InChI

InChI=1S/C21H17FN2O2S/c22-18-8-11-20-17(12-18)13-21(23-20)16-6-9-19(10-7-16)24-27(25,26)14-15-4-2-1-3-5-15/h1-13,23-24H,14H2

InChI Key

ZILSQNQEPUNZSC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14969820

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.052

Distribution Coefficient, logD

5.043

Water Solubility, LogSw

-5.25

Polar Surface Area

51.593

Acid Dissociation Constant (pKa)

9.05

Base Dissociation Constant (pKb)

-2.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

F878-0294 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Nuclear receptors
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F878-0294 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F878-0294?
Check Price and Availability of F878-0294, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F878-0294 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F878-0294
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F878-0294
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F878-0294 available by request