F912-0373 Screening compound: N-(3-{[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]carbamoyl}phenyl)-5-[(2-methylphenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide

F912-0373 Screening compound: N-(3-{[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]carbamoyl}phenyl)-5-[(2-methylphenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide
F912-0373 Screening compound: N-(3-{[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]carbamoyl}phenyl)-5-[(2-methylphenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F912-0373
N-(3-{[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]carbamoyl}phenyl)-5-[(2-methylphenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F912-0373

Molecular Formula

C25H25N5O4S (C25 H25 N5 O4 S)

Compound Name

N-(3-{[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]carbamoyl}phenyl)-5-[(2-methylphenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide

IUPAC name

N-(3-{[2-(35-dimethyl-12-oxazol-4-yl)ethyl]carbamoyl}phenyl)-5-[(2-methylphenoxy)methyl]-134-thiadiazole-2-carboxamide

SMILES

Cc1noc(C)c1CCNC(c1cccc(NC(c2nnc(COc3c(C)cccc3)s2)=O)c1)=O

InChI

InChI=1S/C25H25N5O4S/c1-15-7-4-5-10-21(15)33-14-22-28-29-25(35-22)24(32)27-19-9-6-8-18(13-19)23(31)26-12-11-20-16(2)30-34-17(20)3/h4-10,13H,11-12,14H2,1-3H3,(H,26,31)(H,27,32)

InChI Key

SFYWHWJMKJTWIC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14970442

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.57

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.717

Distribution Coefficient, logD

3.717

Water Solubility, LogSw

-4.19

Polar Surface Area

100.936

Acid Dissociation Constant (pKa)

11.03

Base Dissociation Constant (pKb)

-0.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

F912-0373 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F912-0373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F912-0373?
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What is the minimum amount of F912-0373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F912-0373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F912-0373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F912-0373 available by request