F919-0296 Screening compound: N-methyl-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-4-(piperazin-1-yl)-3-(thiophene-2-sulfonamido)benzamide

F919-0296 Screening compound: N-methyl-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-4-(piperazin-1-yl)-3-(thiophene-2-sulfonamido)benzamide
F919-0296 Screening compound: N-methyl-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-4-(piperazin-1-yl)-3-(thiophene-2-sulfonamido)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F919-0296
N-methyl-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-4-(piperazin-1-yl)-3-(thiophene-2-sulfonamido)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F919-0296

Molecular Formula

C22H29N5O4S2 (C22 H29 N5 O4 S2)

Compound Name

N-methyl-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-4-(piperazin-1-yl)-3-(thiophene-2-sulfonamido)benzamide

IUPAC name

N-methyl-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-4-(piperazin-1-yl)-3-(thiophene-2-sulfonamido)benzamide

SMILES

CN(CC(N1CCCC1)=O)C(c(cc1)cc(NS(c2cccs2)(=O)=O)c1N1CCNCC1)=O

InChI

InChI=1S/C22H29N5O4S2/c1-25(16-20(28)27-10-2-3-11-27)22(29)17-6-7-19(26-12-8-23-9-13-26)18(15-17)24-33(30,31)21-5-4-14-32-21/h4-7,14-15,23-24H,2-3,8-13,16H2,1H3

InChI Key

FMTQSEXHFBEPDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14971747

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

491.64

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.958

Distribution Coefficient, logD

0.958

Water Solubility, LogSw

-2.45

Polar Surface Area

89.230

Acid Dissociation Constant (pKa)

7.10

Base Dissociation Constant (pKb)

8.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

F919-0296 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F919-0296 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F919-0296?
Check Price and Availability of F919-0296, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F919-0296 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F919-0296
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F919-0296
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F919-0296 available by request