F951-0868 Screening compound: 1-cyclopropanecarbonyl-5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole

F951-0868 Screening compound: 1-cyclopropanecarbonyl-5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole
F951-0868 Screening compound: 1-cyclopropanecarbonyl-5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound F951-0868
1-cyclopropanecarbonyl-5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F951-0868

Molecular Formula

C25H29N3O2 (C25 H29 N3 O2)

Compound Name

1-cyclopropanecarbonyl-5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole

IUPAC name

1-cyclopropanecarbonyl-5-[4-(23-dimethylphenyl)piperazine-1-carbonyl]-23-dihydro-1H-indole

SMILES

Cc1cccc(N(CC2)CCN2C(c(cc2)cc(CC3)c2N3C(C2CC2)=O)=O)c1C

InChI

InChI=1S/C25H29N3O2/c1-17-4-3-5-22(18(17)2)26-12-14-27(15-13-26)24(29)21-8-9-23-20(16-21)10-11-28(23)25(30)19-6-7-19/h3-5,8-9,16,19H,6-7,10-15H2,1-2H3

InChI Key

SOLVEDXFYFSOKD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27205745

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.072

Distribution Coefficient, logD

4.072

Water Solubility, LogSw

-4.19

Polar Surface Area

36.048

Acid Dissociation Constant (pKa)

21.07

Base Dissociation Constant (pKb)

4.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

F951-0868 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F951-0868 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F951-0868?
Check Price and Availability of F951-0868, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F951-0868 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F951-0868
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F951-0868
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F951-0868 available by request