G008-0675 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-N-(4-ethylphenyl)piperidine-4-carboxamide

G008-0675 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-N-(4-ethylphenyl)piperidine-4-carboxamide
G008-0675 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-N-(4-ethylphenyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G008-0675
1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-N-(4-ethylphenyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G008-0675

Molecular Formula

C27H33N3O3S (C27 H33 N3 O3 S)

Compound Name

1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-N-(4-ethylphenyl)piperidine-4-carboxamide

IUPAC name

1-{5H6H7H8H9H10H-cyclohepta[b]indole-2-sulfonyl}-N-(4-ethylphenyl)piperidine-4-carboxamide

SMILES

CCc(cc1)ccc1NC(C(CC1)CCN1S(c(cc1)cc2c1[nH]c1c2CCCCC1)(=O)=O)=O

InChI

InChI=1S/C27H33N3O3S/c1-2-19-8-10-21(11-9-19)28-27(31)20-14-16-30(17-15-20)34(32,33)22-12-13-26-24(18-22)23-6-4-3-5-7-25(23)29-26/h8-13,18,20,29H,2-7,14-17H2,1H3,(H,28,31)

InChI Key

VGAWAJKTGWOFMJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14974399

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.64

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.982

Distribution Coefficient, logD

4.982

Water Solubility, LogSw

-4.61

Polar Surface Area

66.142

Acid Dissociation Constant (pKa)

11.95

Base Dissociation Constant (pKb)

2.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

G008-0675 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G008-0675 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G008-0675?
Check Price and Availability of G008-0675, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G008-0675 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G008-0675
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G008-0675
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G008-0675 available by request