G115-0221 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzene-1-sulfonamide

G115-0221 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
G115-0221 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G115-0221
N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G115-0221

Molecular Formula

C24H28FN3O3S (C24 H28 FN3 O3 S)

Compound Name

N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzene-1-sulfonamide

IUPAC name

N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-methyl-5-(3-methyl-12-oxazol-5-yl)benzene-1-sulfonamide

SMILES

Cc1noc(-c2cc(S(NCC3CCN(Cc(cccc4)c4F)CC3)(=O)=O)c(C)cc2)c1

InChI

InChI=1S/C24H28FN3O3S/c1-17-7-8-20(23-13-18(2)27-31-23)14-24(17)32(29,30)26-15-19-9-11-28(12-10-19)16-21-5-3-4-6-22(21)25/h3-8,13-14,19,26H,9-12,15-16H2,1-2H3

InChI Key

FXEYUBCEWXHJAV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14980795

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.892

Distribution Coefficient, logD

3.519

Water Solubility, LogSw

-4.63

Polar Surface Area

67.071

Acid Dissociation Constant (pKa)

10.79

Base Dissociation Constant (pKb)

8.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

G115-0221 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

CNS targets activity set (6557 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G115-0221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G115-0221?
Check Price and Availability of G115-0221, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G115-0221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G115-0221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G115-0221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G115-0221 available by request