G122-1411 Screening compound: 5-[3,4-dihydro-1(2H)-quinolinyl]-N~2~-[3-(4-ethylpiperazino)propyl]-2-thiophenecarboxamide

G122-1411 Screening compound: 5-[3,4-dihydro-1(2H)-quinolinyl]-N~2~-[3-(4-ethylpiperazino)propyl]-2-thiophenecarboxamide
G122-1411 Screening compound: 5-[3,4-dihydro-1(2H)-quinolinyl]-N~2~-[3-(4-ethylpiperazino)propyl]-2-thiophenecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G122-1411
5-[3,4-dihydro-1(2H)-quinolinyl]-N~2~-[3-(4-ethylpiperazino)propyl]-2-thiophenecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G122-1411

Molecular Formula

C23H32N4OS (C23 H32 N4 OS)

Compound Name

5-[3,4-dihydro-1(2H)-quinolinyl]-N~2~-[3-(4-ethylpiperazino)propyl]-2-thiophenecarboxamide

IUPAC name

N-[3-(4-ethylpiperazin-1-yl)propyl]-5-(1234-tetrahydroquinolin-1-yl)thiophene-2-carboxamide

SMILES

CCN1CCN(CCCNC(c2ccc(N(CCC3)c4c3cccc4)s2)=O)CC1

InChI

InChI=1S/C23H32N4OS/c1-2-25-15-17-26(18-16-25)13-6-12-24-23(28)21-10-11-22(29-21)27-14-5-8-19-7-3-4-9-20(19)27/h3-4,7,9-11H,2,5-6,8,12-18H2,1H3,(H,24,28)

InChI Key

JBTNZYVCFJPMRH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14982433

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.6

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.517

Distribution Coefficient, logD

2.568

Water Solubility, LogSw

-3.65

Polar Surface Area

35.499

Acid Dissociation Constant (pKa)

15.79

Base Dissociation Constant (pKb)

8.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.17

G122-1411 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with G122-1411 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G122-1411?
Check Price and Availability of G122-1411, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G122-1411 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G122-1411
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G122-1411
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G122-1411 available by request