G206-1580 Screening compound: 5-(4-isopropylphenyl)-4-methyl-2-{2-oxo-2-[4-(2-pyridyl)piperazino]ethyl}-1H-1lambda~6~-isothiazole-1,1,3(2H)-trione

G206-1580 Screening compound: 5-(4-isopropylphenyl)-4-methyl-2-{2-oxo-2-[4-(2-pyridyl)piperazino]ethyl}-1H-1lambda~6~-isothiazole-1,1,3(2H)-trione
G206-1580 Screening compound: 5-(4-isopropylphenyl)-4-methyl-2-{2-oxo-2-[4-(2-pyridyl)piperazino]ethyl}-1H-1lambda~6~-isothiazole-1,1,3(2H)-trione alternative view

Chemical Structure Depiction of ChemDiv screening compound G206-1580
5-(4-isopropylphenyl)-4-methyl-2-{2-oxo-2-[4-(2-pyridyl)piperazino]ethyl}-1H-1lambda~6~-isothiazole-1,1,3(2H)-trione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G206-1580

Molecular Formula

C24H28N4O4S (C24 H28 N4 O4 S)

Compound Name

5-(4-isopropylphenyl)-4-methyl-2-{2-oxo-2-[4-(2-pyridyl)piperazino]ethyl}-1H-1lambda~6~-isothiazole-1,1,3(2H)-trione

IUPAC name

4-methyl-2-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-5-[4-(propan-2-yl)phenyl]-23-dihydro-1lambda62-thiazole-113-trione

SMILES

CC(C)c(cc1)ccc1C(S(N1CC(N(CC2)CCN2c2ncccc2)=O)(=O)=O)=C(C)C1=O

InChI

InChI=1S/C24H28N4O4S/c1-17(2)19-7-9-20(10-8-19)23-18(3)24(30)28(33(23,31)32)16-22(29)27-14-12-26(13-15-27)21-6-4-5-11-25-21/h4-11,17H,12-16H2,1-3H3

InChI Key

IJNCKBKPGQYOSS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14985778

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.166

Distribution Coefficient, logD

3.157

Water Solubility, LogSw

-3.21

Polar Surface Area

73.348

Acid Dissociation Constant (pKa)

21.40

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

G206-1580 in Drug Discovery

Included in Screening Libraries

Nucleoside Mimetics Library (2197 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Cancer
  • Immune system
  • Immune system
Structure:
  • Mimetics
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G206-1580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G206-1580?
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What is the minimum amount of G206-1580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G206-1580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G206-1580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G206-1580 available by request