G208-0184 Screening compound: 1,3-benzodioxol-5-yl[4-hydroxy-4-(1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-yl)piperidino]methanone

G208-0184 Screening compound: 1,3-benzodioxol-5-yl[4-hydroxy-4-(1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-yl)piperidino]methanone
G208-0184 Screening compound: 1,3-benzodioxol-5-yl[4-hydroxy-4-(1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-yl)piperidino]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound G208-0184
1,3-benzodioxol-5-yl[4-hydroxy-4-(1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-yl)piperidino]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G208-0184

Molecular Formula

C24H25N3O4 (C24 H25 N3 O4)

Compound Name

1,3-benzodioxol-5-yl[4-hydroxy-4-(1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-yl)piperidino]methanone

IUPAC name

n/a

SMILES

OC(CC1)(CCN1C(c(cc1)cc2c1OCO2)=O)C(CCN1C2)C1=Nc1c2cccc1

InChI

InChI=1S/C24H25N3O4/c28-23(16-5-6-20-21(13-16)31-15-30-20)26-11-8-24(29,9-12-26)18-7-10-27-14-17-3-1-2-4-19(17)25-22(18)27/h1-6,13,18,29H,7-12,14-15H2/t18-/m1/s1

InChI Key

AAZGVISJEQDCKF-GOSISDBHSA-N

MDL Number (MFCD)

MFCD14986242

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.299

Distribution Coefficient, logD

0.593

Water Solubility, LogSw

-2.65

Polar Surface Area

61.230

Acid Dissociation Constant (pKa)

15.87

Base Dissociation Constant (pKb)

9.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

G208-0184 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G208-0184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G208-0184?
Check Price and Availability of G208-0184, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G208-0184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G208-0184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G208-0184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G208-0184 available by request