G209-0089 Screening compound: 4-[2-(4-chlorophenyl)-3,4-dimethyl-2H-pyrazolo[3,4-d]pyridazin-7-yl]-N-(2,5-difluorophenyl)piperazine-1-carboxamide

G209-0089 Screening compound: 4-[2-(4-chlorophenyl)-3,4-dimethyl-2H-pyrazolo[3,4-d]pyridazin-7-yl]-N-(2,5-difluorophenyl)piperazine-1-carboxamide
G209-0089 Screening compound: 4-[2-(4-chlorophenyl)-3,4-dimethyl-2H-pyrazolo[3,4-d]pyridazin-7-yl]-N-(2,5-difluorophenyl)piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G209-0089
4-[2-(4-chlorophenyl)-3,4-dimethyl-2H-pyrazolo[3,4-d]pyridazin-7-yl]-N-(2,5-difluorophenyl)piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G209-0089

Molecular Formula

C24H22ClF2N7O (C24 H22 ClF2 N7 O)

Compound Name

4-[2-(4-chlorophenyl)-3,4-dimethyl-2H-pyrazolo[3,4-d]pyridazin-7-yl]-N-(2,5-difluorophenyl)piperazine-1-carboxamide

IUPAC name

4-[2-(4-chlorophenyl)-34-dimethyl-2H-pyrazolo[34-d]pyridazin-7-yl]-N-(25-difluorophenyl)piperazine-1-carboxamide

SMILES

Cc(n(-c(cc1)ccc1Cl)nc12)c2c(C)nnc1N(CC1)CCN1C(Nc(cc(cc1)F)c1F)=O

InChI

InChI=1S/C24H22ClF2N7O/c1-14-21-15(2)34(18-6-3-16(25)4-7-18)31-22(21)23(30-29-14)32-9-11-33(12-10-32)24(35)28-20-13-17(26)5-8-19(20)27/h3-8,13H,9-12H2,1-2H3,(H,28,35)

InChI Key

DXVMVOMCKJUKEQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14986292

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.93

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.595

Distribution Coefficient, logD

4.570

Water Solubility, LogSw

-4.82

Polar Surface Area

64.849

Acid Dissociation Constant (pKa)

10.26

Base Dissociation Constant (pKb)

6.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G209-0089 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

Human Proteases Annotated Library (2868 compounds)

Protein-Protein Interaction Library (218420 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with G209-0089 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G209-0089?
Check Price and Availability of G209-0089, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G209-0089 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G209-0089
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G209-0089
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G209-0089 available by request