G215-1754 Screening compound: N~3~-cyclopentyl-4-(4-ethoxybenzyl)-3-methyl-5-oxo-2,3,4,5-tetrahydro[1]benzofuro[2,3-f][1,4]oxazepine-3-carboxamide

G215-1754 Screening compound: N~3~-cyclopentyl-4-(4-ethoxybenzyl)-3-methyl-5-oxo-2,3,4,5-tetrahydro[1]benzofuro[2,3-f][1,4]oxazepine-3-carboxamide
G215-1754 Screening compound: N~3~-cyclopentyl-4-(4-ethoxybenzyl)-3-methyl-5-oxo-2,3,4,5-tetrahydro[1]benzofuro[2,3-f][1,4]oxazepine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G215-1754
N~3~-cyclopentyl-4-(4-ethoxybenzyl)-3-methyl-5-oxo-2,3,4,5-tetrahydro[1]benzofuro[2,3-f][1,4]oxazepine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G215-1754

Molecular Formula

C27H30N2O5 (C27 H30 N2 O5)

Compound Name

N~3~-cyclopentyl-4-(4-ethoxybenzyl)-3-methyl-5-oxo-2,3,4,5-tetrahydro[1]benzofuro[2,3-f][1,4]oxazepine-3-carboxamide

IUPAC name

n/a

SMILES

CCOc1ccc(CN(C(C)(COc2c3oc4c2cccc4)C(NC2CCCC2)=O)C3=O)cc1

InChI

InChI=1S/C27H30N2O5/c1-3-32-20-14-12-18(13-15-20)16-29-25(30)24-23(21-10-6-7-11-22(21)34-24)33-17-27(29,2)26(31)28-19-8-4-5-9-19/h6-7,10-15,19H,3-5,8-9,16-17H2,1-2H3,(H,28,31)/t27-/m0/s1

InChI Key

UZNBRZQMBRQBGE-MHZLTWQESA-N

MDL Number (MFCD)

MFCD27211001

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.341

Distribution Coefficient, logD

5.341

Water Solubility, LogSw

-5.38

Polar Surface Area

64.173

Acid Dissociation Constant (pKa)

15.33

Base Dissociation Constant (pKb)

1.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.70

G215-1754 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

Cyclic Ugi PPI Library (9586 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Developmental Pathway (Hh/Wnt) Set (2238 compounds)

Peptidomimetic Library (37031 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Others
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G215-1754 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G215-1754?
Check Price and Availability of G215-1754, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G215-1754 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G215-1754
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G215-1754
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G215-1754 available by request