G221-0197 Screening compound: ({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]amine

G221-0197 Screening compound: ({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]amine
G221-0197 Screening compound: ({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G221-0197
({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G221-0197

Molecular Formula

C28H28ClFN4O (C28 H28 ClFN4 O)

Compound Name

({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]amine

IUPAC name

({1-[(4-chlorophenyl)methyl]piperidin-4-yl}methyl)[(4-fluorophenyl)(5-phenyl-134-oxadiazol-2-yl)methyl]amine

SMILES

Fc1ccc(C(c2nnc(-c3ccccc3)o2)NCC2CCN(Cc(cc3)ccc3Cl)CC2)cc1

InChI

InChI=1S/C28H28ClFN4O/c29-24-10-6-21(7-11-24)19-34-16-14-20(15-17-34)18-31-26(22-8-12-25(30)13-9-22)28-33-32-27(35-28)23-4-2-1-3-5-23/h1-13,20,26,31H,14-19H2/t26-/m1/s1

InChI Key

ATEFTIKCLNZSBH-AREMUKBSSA-N

MDL Number (MFCD)

MFCD14988499

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.01

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.450

Distribution Coefficient, logD

3.885

Water Solubility, LogSw

-6.39

Polar Surface Area

45.124

Acid Dissociation Constant (pKa)

23.49

Base Dissociation Constant (pKb)

8.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.60

G221-0197 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • GPCR
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with G221-0197 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G221-0197?
Check Price and Availability of G221-0197, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G221-0197 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G221-0197
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G221-0197
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G221-0197 available by request