G234-0139 Screening compound: 1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-[3-(trifluoromethyl)phenyl]piperazine

G234-0139 Screening compound: 1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-[3-(trifluoromethyl)phenyl]piperazine
G234-0139 Screening compound: 1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-[3-(trifluoromethyl)phenyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G234-0139
1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-[3-(trifluoromethyl)phenyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G234-0139

Molecular Formula

C26H22ClF3N4O (C26 H22 ClF3 N4 O)

Compound Name

1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-[3-(trifluoromethyl)phenyl]piperazine

IUPAC name

1-{[5-(2-chlorophenyl)-134-oxadiazol-2-yl](phenyl)methyl}-4-[3-(trifluoromethyl)phenyl]piperazine

SMILES

FC(c1cccc(N(CC2)CCN2C(c2nnc(-c(cccc3)c3Cl)o2)c2ccccc2)c1)(F)F

InChI

InChI=1S/C26H22ClF3N4O/c27-22-12-5-4-11-21(22)24-31-32-25(35-24)23(18-7-2-1-3-8-18)34-15-13-33(14-16-34)20-10-6-9-19(17-20)26(28,29)30/h1-12,17,23H,13-16H2/t23-/m1/s1

InChI Key

WTBKOXCDAQQCGN-HSZRJFAPSA-N

MDL Number (MFCD)

MFCD12129680

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.93

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.142

Distribution Coefficient, logD

6.142

Water Solubility, LogSw

-6.33

Polar Surface Area

36.768

Acid Dissociation Constant (pKa)

26.69

Base Dissociation Constant (pKb)

6.48

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.10

G234-0139 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with G234-0139 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G234-0139?
Check Price and Availability of G234-0139, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G234-0139 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G234-0139
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G234-0139
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G234-0139 available by request