G243-0588 Screening compound: 2-methyl-1-{[1,2,5-trimethyl-4-(piperidine-1-carbonyl)-1H-pyrrol-3-yl]sulfonyl}-2,3-dihydro-1H-indole

G243-0588 Screening compound: 2-methyl-1-{[1,2,5-trimethyl-4-(piperidine-1-carbonyl)-1H-pyrrol-3-yl]sulfonyl}-2,3-dihydro-1H-indole
G243-0588 Screening compound: 2-methyl-1-{[1,2,5-trimethyl-4-(piperidine-1-carbonyl)-1H-pyrrol-3-yl]sulfonyl}-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound G243-0588
2-methyl-1-{[1,2,5-trimethyl-4-(piperidine-1-carbonyl)-1H-pyrrol-3-yl]sulfonyl}-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G243-0588

Molecular Formula

C22H29N3O3S (C22 H29 N3 O3 S)

Compound Name

2-methyl-1-{[1,2,5-trimethyl-4-(piperidine-1-carbonyl)-1H-pyrrol-3-yl]sulfonyl}-2,3-dihydro-1H-indole

IUPAC name

2-methyl-1-{[125-trimethyl-4-(piperidine-1-carbonyl)-1H-pyrrol-3-yl]sulfonyl}-23-dihydro-1H-indole

SMILES

CC(Cc1c2cccc1)N2S(c1c(C)n(C)c(C)c1C(N1CCCCC1)=O)(=O)=O

InChI

InChI=1S/C22H29N3O3S/c1-15-14-18-10-6-7-11-19(18)25(15)29(27,28)21-17(3)23(4)16(2)20(21)22(26)24-12-8-5-9-13-24/h6-7,10-11,15H,5,8-9,12-14H2,1-4H3/t15-/m0/s1

InChI Key

PSMLSAFLKWMIHV-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD14989982

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.871

Distribution Coefficient, logD

2.871

Water Solubility, LogSw

-3.38

Polar Surface Area

50.900

Acid Dissociation Constant (pKa)

26.25

Base Dissociation Constant (pKb)

-2.83

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

G243-0588 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Digestive system
  • Nervous system
Targets:
  • GPCR
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G243-0588 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G243-0588?
Check Price and Availability of G243-0588, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G243-0588 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G243-0588
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G243-0588
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G243-0588 available by request