G261-0135 Screening compound: 2,2,6-trimethyl-7-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3,4,9-tetrahydro-1H-carbazol-4-one

G261-0135 Screening compound: 2,2,6-trimethyl-7-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3,4,9-tetrahydro-1H-carbazol-4-one
G261-0135 Screening compound: 2,2,6-trimethyl-7-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3,4,9-tetrahydro-1H-carbazol-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G261-0135
2,2,6-trimethyl-7-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3,4,9-tetrahydro-1H-carbazol-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G261-0135

Molecular Formula

C24H28N4O3S (C24 H28 N4 O3 S)

Compound Name

2,2,6-trimethyl-7-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3,4,9-tetrahydro-1H-carbazol-4-one

IUPAC name

226-trimethyl-7-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2349-tetrahydro-1H-carbazol-4-one

SMILES

CC(C)(Cc([nH]c1c2)c3c1cc(C)c2S(N(CC1)CCN1c1ncccc1)(=O)=O)CC3=O

InChI

InChI=1S/C24H28N4O3S/c1-16-12-17-18(26-19-14-24(2,3)15-20(29)23(17)19)13-21(16)32(30,31)28-10-8-27(9-11-28)22-6-4-5-7-25-22/h4-7,12-13,26H,8-11,14-15H2,1-3H3

InChI Key

ZJZSTGFKEAOYHD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14990305

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.614

Distribution Coefficient, logD

3.590

Water Solubility, LogSw

-4.02

Polar Surface Area

67.739

Acid Dissociation Constant (pKa)

16.15

Base Dissociation Constant (pKb)

6.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

G261-0135 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G261-0135 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G261-0135?
Check Price and Availability of G261-0135, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G261-0135 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G261-0135
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G261-0135
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G261-0135 available by request