G266-0376 Screening compound: 3-(2-CHLOROPHENYL)-N-[1,4-DIMETHYL-2,3-DIOXO-7-(PYRROLIDIN-1-YL)-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL]-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE

G266-0376 Screening compound: 3-(2-CHLOROPHENYL)-N-[1,4-DIMETHYL-2,3-DIOXO-7-(PYRROLIDIN-1-YL)-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL]-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE
G266-0376 Screening compound: 3-(2-CHLOROPHENYL)-N-[1,4-DIMETHYL-2,3-DIOXO-7-(PYRROLIDIN-1-YL)-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL]-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound G266-0376
3-(2-CHLOROPHENYL)-N-[1,4-DIMETHYL-2,3-DIOXO-7-(PYRROLIDIN-1-YL)-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL]-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G266-0376

Molecular Formula

C25H24ClN5O4 (C25 H24 ClN5 O4)

Compound Name

3-(2-CHLOROPHENYL)-N-[1,4-DIMETHYL-2,3-DIOXO-7-(PYRROLIDIN-1-YL)-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL]-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE

IUPAC name

n/a

SMILES

Cc1c(C(Nc(cc(c(N(C)C2=O)c3)N(C)C2=O)c3N2CCCC2)=O)c(-c(cccc2)c2Cl)no1

InChI

InChI=1S/C25H24ClN5O4/c1-14-21(22(28-35-14)15-8-4-5-9-16(15)26)23(32)27-17-12-19-20(13-18(17)31-10-6-7-11-31)30(3)25(34)24(33)29(19)2/h4-5,8-9,12-13H,6-7,10-11H2,1-3H3,(H,27,32)

InChI Key

FAKRLZZHRTUYOP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27211687

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.95

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.205

Distribution Coefficient, logD

2.866

Water Solubility, LogSw

-3.96

Polar Surface Area

78.469

Acid Dissociation Constant (pKa)

7.33

Base Dissociation Constant (pKb)

0.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

G266-0376 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G266-0376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G266-0376?
Check Price and Availability of G266-0376, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G266-0376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G266-0376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G266-0376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G266-0376 available by request