G267-0820 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(4-ethylphenyl)methyl]propanamide

G267-0820 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(4-ethylphenyl)methyl]propanamide
G267-0820 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(4-ethylphenyl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G267-0820
3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(4-ethylphenyl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G267-0820

Molecular Formula

C25H32N6O (C25 H32 N6 O)

Compound Name

3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(4-ethylphenyl)methyl]propanamide

IUPAC name

3-{35-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(4-ethylphenyl)methyl]propanamide

SMILES

CCc1ccc(CNC(CCc2c(C)n(-c(cc3)nnc3N3CCCC3)nc2C)=O)cc1

InChI

InChI=1S/C25H32N6O/c1-4-20-7-9-21(10-8-20)17-26-25(32)14-11-22-18(2)29-31(19(22)3)24-13-12-23(27-28-24)30-15-5-6-16-30/h7-10,12-13H,4-6,11,14-17H2,1-3H3,(H,26,32)

InChI Key

APEOVVOEDXMZJI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992273

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.823

Distribution Coefficient, logD

3.771

Water Solubility, LogSw

-3.90

Polar Surface Area

63.345

Acid Dissociation Constant (pKa)

12.87

Base Dissociation Constant (pKb)

6.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

G267-0820 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antiviral Library (67538 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G267-0820 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G267-0820?
Check Price and Availability of G267-0820, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G267-0820 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G267-0820
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G267-0820
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G267-0820 available by request