G274-0093 Screening compound: 2-{1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

G274-0093 Screening compound: 2-{1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline
G274-0093 Screening compound: 2-{1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G274-0093
2-{1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G274-0093

Molecular Formula

C23H24N4OS (C23 H24 N4 OS)

Compound Name

2-{1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-{1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carbonyl}-1234-tetrahydroisoquinoline

SMILES

O=C(C(CC1)CCN1c(cc1)nnc1-c1cccs1)N(CC1)Cc2c1cccc2

InChI

InChI=1S/C23H24N4OS/c28-23(27-14-9-17-4-1-2-5-19(17)16-27)18-10-12-26(13-11-18)22-8-7-20(24-25-22)21-6-3-15-29-21/h1-8,15,18H,9-14,16H2

InChI Key

PUJFVVBMCWCCPK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992787

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.093

Distribution Coefficient, logD

4.093

Water Solubility, LogSw

-4.16

Polar Surface Area

41.954

Acid Dissociation Constant (pKa)

22.38

Base Dissociation Constant (pKb)

3.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

G274-0093 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G274-0093 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G274-0093?
Check Price and Availability of G274-0093, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G274-0093 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G274-0093
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G274-0093
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G274-0093 available by request