G274-0140 Screening compound: 3-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-6-(thiophen-2-yl)pyridazine

G274-0140 Screening compound: 3-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-6-(thiophen-2-yl)pyridazine
G274-0140 Screening compound: 3-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-6-(thiophen-2-yl)pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G274-0140
3-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-6-(thiophen-2-yl)pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G274-0140

Molecular Formula

C23H26N6OS (C23 H26 N6 OS)

Compound Name

3-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-6-(thiophen-2-yl)pyridazine

IUPAC name

3-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-6-(thiophen-2-yl)pyridazine

SMILES

O=C(C(CC1)CCN1c(cc1)nnc1-c1cccs1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C23H26N6OS/c30-23(29-15-13-28(14-16-29)21-5-1-2-10-24-21)18-8-11-27(12-9-18)22-7-6-19(25-26-22)20-4-3-17-31-20/h1-7,10,17-18H,8-9,11-16H2

InChI Key

PRLIKUHBBJAUEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992818

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.514

Distribution Coefficient, logD

3.505

Water Solubility, LogSw

-3.41

Polar Surface Area

54.064

Acid Dissociation Constant (pKa)

22.96

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G274-0140 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with G274-0140 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G274-0140?
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What is the minimum amount of G274-0140 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G274-0140
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G274-0140
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G274-0140 available by request