G274-1208 Screening compound: 1-[6-(5-bromothiophen-2-yl)pyridazin-3-yl]-N-[2-(3-methylthiophen-2-yl)ethyl]piperidine-4-carboxamide

G274-1208 Screening compound: 1-[6-(5-bromothiophen-2-yl)pyridazin-3-yl]-N-[2-(3-methylthiophen-2-yl)ethyl]piperidine-4-carboxamide
G274-1208 Screening compound: 1-[6-(5-bromothiophen-2-yl)pyridazin-3-yl]-N-[2-(3-methylthiophen-2-yl)ethyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G274-1208
1-[6-(5-bromothiophen-2-yl)pyridazin-3-yl]-N-[2-(3-methylthiophen-2-yl)ethyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G274-1208

Molecular Formula

C21H23BrN4OS2 (C21 H23 BrN4 OS2)

Compound Name

1-[6-(5-bromothiophen-2-yl)pyridazin-3-yl]-N-[2-(3-methylthiophen-2-yl)ethyl]piperidine-4-carboxamide

IUPAC name

1-[6-(5-bromothiophen-2-yl)pyridazin-3-yl]-N-[2-(3-methylthiophen-2-yl)ethyl]piperidine-4-carboxamide

SMILES

Cc1c(CCNC(C(CC2)CCN2c(cc2)nnc2-c(s2)ccc2Br)=O)scc1

InChI

InChI=1S/C21H23BrN4OS2/c1-14-9-13-28-17(14)6-10-23-21(27)15-7-11-26(12-8-15)20-5-2-16(24-25-20)18-3-4-19(22)29-18/h2-5,9,13,15H,6-8,10-12H2,1H3,(H,23,27)

InChI Key

UCDFUBHIYWOUFJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992992

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.768

Distribution Coefficient, logD

4.768

Water Solubility, LogSw

-4.36

Polar Surface Area

50.917

Acid Dissociation Constant (pKa)

14.07

Base Dissociation Constant (pKb)

3.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

G274-1208 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G274-1208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G274-1208?
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What is the minimum amount of G274-1208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G274-1208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G274-1208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G274-1208 available by request