G275-1344 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-[3-(trifluoromethyl)phenyl]piperazine

G275-1344 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-[3-(trifluoromethyl)phenyl]piperazine
G275-1344 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-[3-(trifluoromethyl)phenyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G275-1344
1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-[3-(trifluoromethyl)phenyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G275-1344

Molecular Formula

C20H21F3N4O2S2 (C20 H21 F3 N4 O2 S2)

Compound Name

1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-[3-(trifluoromethyl)phenyl]piperazine

IUPAC name

1-{[5-(34-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-[3-(trifluoromethyl)phenyl]piperazine

SMILES

Cc1c(-c(s2)ccc2S(N(CC2)CCN2c2cc(C(F)(F)F)ccc2)(=O)=O)[nH]nc1C

InChI

InChI=1S/C20H21F3N4O2S2/c1-13-14(2)24-25-19(13)17-6-7-18(30-17)31(28,29)27-10-8-26(9-11-27)16-5-3-4-15(12-16)20(21,22)23/h3-7,12H,8-11H2,1-2H3,(H,24,25)

InChI Key

QPSBHAQBXHNZKW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993161

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.415

Distribution Coefficient, logD

4.411

Water Solubility, LogSw

-4.23

Polar Surface Area

60.065

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

5.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

G275-1344 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro

References: we are preparing a list of scientific research reports with G275-1344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G275-1344?
Check Price and Availability of G275-1344, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G275-1344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G275-1344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G275-1344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G275-1344 available by request