G275-1388 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-ethylpiperazine

G275-1388 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-ethylpiperazine
G275-1388 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-ethylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G275-1388
1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-ethylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G275-1388

Molecular Formula

C15H22N4O2S2 (C15 H22 N4 O2 S2)

Compound Name

1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-ethylpiperazine

IUPAC name

1-{[5-(34-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-ethylpiperazine

SMILES

CCN(CC1)CCN1S(c1ccc(-c2c(C)c(C)n[nH]2)s1)(=O)=O

InChI

InChI=1S/C15H22N4O2S2/c1-4-18-7-9-19(10-8-18)23(20,21)14-6-5-13(22-14)15-11(2)12(3)16-17-15/h5-6H,4,7-10H2,1-3H3,(H,16,17)

InChI Key

UAYGRGFQWFZRLG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993178

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.141

Distribution Coefficient, logD

2.020

Water Solubility, LogSw

-2.64

Polar Surface Area

60.342

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

6.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

53.30

G275-1388 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G275-1388 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G275-1388?
Check Price and Availability of G275-1388, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G275-1388 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G275-1388
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G275-1388
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G275-1388 available by request