G275-1413 Screening compound: 4-[6-(4-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyridazin-3-yl]morpholine

G275-1413 Screening compound: 4-[6-(4-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyridazin-3-yl]morpholine
G275-1413 Screening compound: 4-[6-(4-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyridazin-3-yl]morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound G275-1413
4-[6-(4-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyridazin-3-yl]morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G275-1413

Molecular Formula

C21H27N7O3S2 (C21 H27 N7 O3 S2)

Compound Name

4-[6-(4-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyridazin-3-yl]morpholine

IUPAC name

4-[6-(4-{[5-(34-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyridazin-3-yl]morpholine

SMILES

Cc1c(-c(s2)ccc2S(N(CC2)CCN2c(cc2)nnc2N2CCOCC2)(=O)=O)[nH]nc1C

InChI

InChI=1S/C21H27N7O3S2/c1-15-16(2)22-25-21(15)17-3-6-20(32-17)33(29,30)28-9-7-26(8-10-28)18-4-5-19(24-23-18)27-11-13-31-14-12-27/h3-6H,7-14H2,1-2H3,(H,22,25)

InChI Key

YKKXKGMKHPABBF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993187

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.62

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.741

Distribution Coefficient, logD

2.737

Water Solubility, LogSw

-3.14

Polar Surface Area

92.096

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

5.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

G275-1413 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G275-1413 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G275-1413?
Check Price and Availability of G275-1413, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G275-1413 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G275-1413
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G275-1413
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G275-1413 available by request