G275-1729 Screening compound: 1-({5-[3-(trifluoromethyl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,2,3,4-tetrahydroquinoline

G275-1729 Screening compound: 1-({5-[3-(trifluoromethyl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,2,3,4-tetrahydroquinoline
G275-1729 Screening compound: 1-({5-[3-(trifluoromethyl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,2,3,4-tetrahydroquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G275-1729
1-({5-[3-(trifluoromethyl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,2,3,4-tetrahydroquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G275-1729

Molecular Formula

C17H14F3N3O2S2 (C17 H14 F3 N3 O2 S2)

Compound Name

1-({5-[3-(trifluoromethyl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,2,3,4-tetrahydroquinoline

IUPAC name

1-({5-[3-(trifluoromethyl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1234-tetrahydroquinoline

SMILES

O=S(c1ccc(-c2cc(C(F)(F)F)n[nH]2)s1)(N(CCC1)c2c1cccc2)=O

InChI

InChI=1S/C17H14F3N3O2S2/c18-17(19,20)15-10-12(21-22-15)14-7-8-16(26-14)27(24,25)23-9-3-5-11-4-1-2-6-13(11)23/h1-2,4,6-8,10H,3,5,9H2,(H,21,22)

InChI Key

XNCWHNQWNIKINX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27212358

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.318

Distribution Coefficient, logD

4.318

Water Solubility, LogSw

-4.31

Polar Surface Area

54.899

Acid Dissociation Constant (pKa)

6.49

Base Dissociation Constant (pKb)

-1.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

G275-1729 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G275-1729 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G275-1729?
Check Price and Availability of G275-1729, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G275-1729 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G275-1729
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G275-1729
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G275-1729 available by request